Whole Genome Sequencing

Whole genome sequencing (WGS) is a comprehensive method for analysing entire genomes which can identify DNA biomarkers such as single nucleotide polymorphism (SNPs), insertions and deletions (indels), structure variations (SVs), copy number variations (CNVs) and other genetic changes of the sequenced species with high accuracy.

It is also an indispensable part of genome wide association study (GWAS), where common genetic variants indifferent individuals are assessed to determine if a variant is associated with a particular phenotype.

GWAS can be broadly used in food safety, agriculture, pharmacy and personalized medicine. What’s more, it provides an unprecedented opportunity for characterizing the polymorphic variants in a population, which comprehensively unravels the underlying mechanisms of species origin, development, growth, and evolution.

Bio Basic Asia Pacific provides both illumina and Nanopore platforms to provide a fast and accurate whole genome sequencing and bioinformatics analysis for any species.

Our highly experienced expert team executes quality management, following every procedure to ensure reliable results.

Bioinformatics Analysis

  • Data Quality Control
  • Alignment with reference genome
  • Variant (SNP, CNV, InDel, and SV) calling, annotation, and statistics

(More analysis upon request)

Advantages

  • Single base-pair resolution
  • Genome-wide mutation characterization
  • Population evolution and phylogenetic studies

Sequencing Platforms 

HiSeq 4000/ HiSeq X Ten/ NovaSeq 6000/ Pabio Sequel/ Nanopore

Analysis Workflow

For more information, feel free to contact us via NGS@biobasic-asia.com or +65 6928 9042.